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DTSTART:20210314T100000
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DTSTART;TZID=America/Los_Angeles:20220929T120000
DTEND;TZID=America/Los_Angeles:20220929T130000
DTSTAMP:20260513T152701
CREATED:20220624T202639Z
LAST-MODIFIED:20220719T172026Z
UID:30667-1664452800-1664456400@leadersinlight.com
SUMMARY:Errol Arkilic\, Ph. D.
DESCRIPTION:Commercialization and searching for a business model: why is spinning technology out of a lab so challenging? \nAbstract \nIn this talk\, we will explore the four critical challenges of getting technology out of a lab. Dr. Arkilic\, Chief Innovation Officer of UCI has spent his entire career in supporting getting technology out of Academic labs. He has been founder StrataGent Life Sciences\, Inc.\, lead program manager for the NSF SBIR program\, founder of the NSF I-Corps program and founder of M34 Capital\, a venture capital firm in Silicon Valley. \n  \nBiography \nErrol Arkilic is Chief Innovation Officer and Executive Director of University of California\, Irvine Beall Applied Innovation. At UCI\, he leads campus‐wide commercialization activity\, helping researchers turn knowledge into products and services that impact society. Prior to his role at UCI\, he was founder and CEO of M34 Capital. M34 is a private investment company that focuses on seed and early‐stage projects being spun out of academic research labs. He currently sits on three boards: Growcentia\, Inc. NeuroTrainer\, Inc. and Ellis Day Skin Science\, Inc. Previously\, Errol was the founding and lead program director for the National Science Foundation Innovation Corps program (I‐Corps). He led the I‐Corps effort from its inception until July 2013. Prior to this\, he was the lead software and services Program Director for the NSF SBIR program. Before his government service\, Errol was founder and CEO of StrataGent Life Sciences (Acquired by Corium International: CORI) and Manager of Product Engineering at Redwood Microsystems. He has a Ph.D. in Aero/Astro Engineering from MIT. \n  \nREGISTER HERE FOR ZOOM \nREGISTER HERE FOR IN PERSON \n 
URL:https://leadersinlight.com/event/errol-arkilic-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2022/06/Errol-Arkilic_square.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220818T120000
DTEND;TZID=America/Los_Angeles:20220818T130000
DTSTAMP:20260513T152701
CREATED:20220811T162605Z
LAST-MODIFIED:20220811T163904Z
UID:30894-1660824000-1660827600@leadersinlight.com
SUMMARY:Jason B. King\, Ph. D.
DESCRIPTION:  \nLaser Beam Shaping for Surgery and Microbiopsy \nAbstract \nLasers are increasingly being used for surgery in a wide range of medical specialties due to their advantages over alternative\nsurgical tools. Advantages include precise material removal\, limited bleeding\, and delivery through optical fibers enabling use\nin body cavities and for minimally invasive surgeries. Advancements in laser technology including new laser wavelengths and\nhigher power continue to improve the performance and implementation of surgical lasers. Temporal beam shaping\, or pulse\nmodulation\, has been implemented into clinical laser systems to increase efficiency of urological surgeries\, leading to faster\,\nsafer procedures. However\, the precise mechanisms of temporally shaped laser ablation are not fully understood. The effects\nof spatial beam shaping on laser tissue ablation have not previously been explored.\nWe aim to understand the impact of temporal and spatial laser beam on laser ablation to improve the performance and\nincrease the applications of laser surgery. Working towards this aim\, a Ho:YAG laser was temporally and spatially altered and\nthe effects on tissue ablation were explored. We explored the mechanisms of pulse modulated ablation through experiments\non phantoms and native kidney stones. We discovered that increased ablation efficiency by pulse modulation is composition\ndependent. Next\, increased ablation efficiency by altering laser spatial shape was explored. We discovered that shaping the\nlaser beam into an annular shape led to an increase in ablation efficiency in both hard and soft tissues. Finally\, we explored\nthe application of spatially shaped laser ablation for laser microbiopsy to harvest sub-microliter (<1 mm3) tissue samples.\nLaser beam shaping\, pulse energy\, and application of cryogen spray cooling were optimized to successfully harvest tissue\nsections with observable histological features. Harvested tissues were imaged with confocal microscopy and “virtual H&E”\nmethods were used to digitally color the images to mimic H&E stained tissue sections. Laser microbiopsy with virtual H&E is\nminimally invasive\, precise\, and provides images in a fraction of the time of the traditional pathology workflow. \n  \nBiography \nDr. Jason King recently graduated with his PhD in biomedical engineering from the University of Texas at Austin. His work\nfocuses on optimization of laser ablation for surgery and biopsy through temporal and spatial laser beam shaping. This work\nincludes computational modeling and ablation experiments aimed at understanding light tissue interactions involved in laser\nablation. His other research interests include confocal microscopy and Raman spectroscopy for cancer diagnosis and\nmonitoring. \n  \nREGISTER HERE FOR ZOOM \nREGISTER HERE FOR IN PERSON \n 
URL:https://leadersinlight.com/event/jason-b-king-ph-d-2/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2022/08/Jasonbking.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Los_Angeles:20220811T120000
DTEND;TZID=America/Los_Angeles:20220811T130000
DTSTAMP:20260513T152701
CREATED:20220811T163755Z
LAST-MODIFIED:20220811T163919Z
UID:30760-1660219200-1660222800@leadersinlight.com
SUMMARY:Olivia L. Lee\, MD
DESCRIPTION:  \nConfocal Microscopy for the Evaluation of OcularSurface Disease \nAbstract \nDiagnosis and treatment of ocular surface disease represents a large proportion of the average ophthalmologist’s\npractice. However\, this group of conditions is more heterogeneous and complex than the term “dry eye” conveys.\nFurther investigation of the pathophysiologic mechanisms underlying these conditions are underway\, and in vivo\nlaser scanning confocal microscopy (IVCM) has emerged as a suitable\, relatively novel\, minimally invasive tool for\nobtaining high-resolution images of tissues at the cellular level. Using this imaging device\, the in vivo visualization of\nthe human cornea can be employed to study ocular surface disease in a non-invasive manner. The use of IVCM\nprovides a new approach to evaluating the microscopic morphology of the cornea and our group has applied this to\nthe study of a variety of ocular surface diseases including Sjogrens syndrome\, Mucous Membrane Pemphigoid\, drug\ninduced dry eye\, Neurotrophic Keratitis\, Stevens Johnson Syndrome and more. IVCM is a promising technique for\nthe diagnosis\, prognostication\, staging and stratification of ocular surface disease. This talk will highlight the clinical\nand research applicability of this imaging technique as applied to ocular surface diseases. \n  \nBiography \nDr. Olivia L. Lee is a board-certified UCI Health ophthalmologist who specializes in corneal diseases and uveitis. Dr.\nLee received her medical degree from Baylor College of Medicine in Houston\, Texas\, followed by a residency in\nophthalmology from the New York Eye & Ear Infirmary in New York City\, where she also completed a fellowship in\nuveitis and ocular immunology. She completed a fellowship in cornea\, external disease and refractive surgery at the\nUCLA Stein Eye Institute. Before joining UCI Health\, she served as cornea fellowship director at the Doheny Eye\nCenter UCLA.\nDr. Lee’s research focuses on the use of anterior segment ophthalmic imaging to develop new clinical endpoints to\nobjectively characterize disease severity and guide clinical decision-making. Her clinical interests include\ninflammatory eye disease and complex anterior segment surgery. Dr. Lee has performed all types of corneal and\ncataract surgeries. \n  \nREGISTER HERE FOR ZOOM \nREGISTER HERE FOR IN PERSON \n 
URL:https://leadersinlight.com/event/olivia-l-lee-md/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2022/08/Olivia-Lee.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20211216T120000
DTEND;TZID=UTC:20211216T130000
DTSTAMP:20260513T152701
CREATED:20211208T055702Z
LAST-MODIFIED:20211208T055807Z
UID:30087-1639656000-1639659600@leadersinlight.com
SUMMARY:Song Hu\, Ph. D.
DESCRIPTION:Light + Sound: Peering into Brain Function and Metabolism \nAbstract\nExploiting the optical absorption contrast of blood hemoglobin\, photoacoustic microscopy (PAM) is an emerging technology for label-free imaging of the microvasculature\, which plays an essential role in supplying oxygen to the biological tissue and maintaining the metabolic activity in vivo. The multi-parametric PAM developed in Dr. Hu’s lab enables\, for the first time\, comprehensive and quantitative characterization of the microvascular structure\, function\, and associated tissue oxygen metabolism at the microscopic level. In this seminar\, Dr. Hu will present their latest progress on the development of PAM and the integration of PAM with other intravital light microscopy techniques for studying brain function and energy metabolism. \nBiography\nDr. Hu received his B.S. and M.S. degrees in Electronic Engineering from Tsinghua University and Ph.D. degree in Biomedical Engineering from Washington University in St. Louis. His research focuses on the development of photoacoustic and optical technologies for high-resolution structural\, functional\, metabolic\, and molecular imaging in vivo. Dr. Hu has published over 70 peer-reviewed articles in journals including Science\, Nature\, Nature Neuroscience\, and Proceedings of the National Academy of Sciences\, and has delivered over 40 invited talks including a Neurotechnologies plenary talk at Photonics West (2018) and a President’s Symposium keynote talk at Annual Microcirculatory Society Meeting (2018). His publications\, including the 4th and 6th most cited articles in the Journal of Biomedical Optics since 2009 and the 5th most cited article in Optics Letters since 2007\, have accumulated around 9\,000 citations (h-index: 37). Dr. Hu is a recipient of the Ralph E. Powe Junior Faculty Enhancement Award (2014)\, the National Science Foundation Faculty Early Career Development (NSF CAREER) Award (2018)\, and the Chan Zuckerberg Initiative Frontiers of Imaging Award (2020). \nREGISTER HERE \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/song-hu-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/12/Song-Hu.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20211202T120000
DTEND;TZID=UTC:20211202T130000
DTSTAMP:20260513T152701
CREATED:20211130T053721Z
LAST-MODIFIED:20211130T053721Z
UID:30060-1638446400-1638450000@leadersinlight.com
SUMMARY:Wenbin Tan\, Ph. D.
DESCRIPTION:Vasculopathy in COVID-19 and Pathogenesis of Cutaneous Vascular Malformations \nAbstract\nSARS-CoV-2-associated vasculopathy under hyperlipidemia and pathological progression of congenital vascular\nabnormalities in Port Wine Stains. In the first part\, we will present our clinical data for the first discovery of dyslipidemia\nin COVID-19 patients which have been substantially recognized. Mechanistically\, we have shown evidence of niche why\nobese subjects are more vulnerable to SARS-CoV-2 attack. Using a spike protein–pseudotyped (Spp) lentivirus with the\nproper tropism of the SARS-CoV-2 spike protein on the surface\, we have found that Spp lentiviruses preferably attack to\nendothelial cells in heart in obese but not normal weight mice\, leading to exaggerated vasculopathy and cardiomyopathy.\nCells with over-expression of Spike protein have impaired lipid metabolic and autophagy formation pathways\, resulting in\nincreased cell death in response to lipotoxicity. In the second part\, we will discuss the clinical molecular pathology of\ninfantile and early childhood PWS to show that (1) PWS is a disease with pathological alterations involving the entire skin\nphysiological milieu; (2) pluripotent cells with the GNAQ (R183Q) may give rise to multilineages in PWS; and (3) exocytosis\nof extracellular vesicles is enhanced in PWS vasculatures. \nBiography\nDr. Tan received his medical degree and master degree in Molecular Biology from XiangYa School of Medicine\, China. He\nreceived his PhD in neurobiology and neurophysiology from University of California\, Los Angeles. He joined Beckman\nLaser Institute at UC Irvine as an assistant project scientist in 2010 under the mentorship of Dr. Stuart Nelson. In 2018\,\nhe joined the department of cell biology and anatomy at School of Medicine University of South Carolina as an associate\nprofessor. \nREGISTER HERE \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/wenbin-tan-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/11/Wenbin-Tan.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20211014T120000
DTEND;TZID=UTC:20211014T130000
DTSTAMP:20260513T152701
CREATED:20211014T005755Z
LAST-MODIFIED:20211014T010429Z
UID:29834-1634212800-1634216400@leadersinlight.com
SUMMARY:Erin Buckley\, Ph. D.
DESCRIPTION:Illuminating Biomarkers of Stroke with Diffuse Optical Spectroscopies \nAbstract\nOur research group specializes in the development and application of diffuse optical spectroscopies to study the brain. These non-invasive\, light-based tools enable real-time bedside monitoring of microvascular hemodynamics. In this seminar\, I will focus on our recent work that uses these tools to identify biomarkers of stroke risk in two high-risk patient populations; subarachnoid hemorrhage and pediatric sickle cell disease. Moreover\, I will talk about how we have advanced the techniques to account for the confounding influences of hematocrit in the sickle cell cohort. \nBiography\nDr. Buckley is an Assistant Professor in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Institute of Technology and Emory University. She is also an assistant professor at the Department of Pediatrics at Emory University. She received her PhD from the Department of Physics and Astronomy from the University of Pennsylvania in 2011 and completed postdoctoral training at the Children’s Hospital of Philadelphia and at Massachusetts General Hospital. Her research focuses on the development and validation of diffuse optical spectroscopies. \nREGISTER HERE \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/erin-buckley-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/10/Dr-Buckley-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20210819T120000
DTEND;TZID=UTC:20210819T130000
DTSTAMP:20260513T152701
CREATED:20210810T020201Z
LAST-MODIFIED:20210810T020417Z
UID:29697-1629374400-1629378000@leadersinlight.com
SUMMARY:Stacy Copp\, Ph. D.
DESCRIPTION:Fluorophores with a Genome: DNA-Stabilized Silver Clusters as a New Class of Tunable Fluorophores for Microscopy and Biosensing \nAbstract\nBecause near-infrared (NIR) electromagnetic radiation penetrates much farther into biological tissues than visible light\, NIR microscopy allows for noninvasive imaging deep into tissues and even whole organisms. In the second near-infrared window (NIR-II: 1\,000-1\,700 nm)\, biological tissues are transparent up to several centimeters depth. However\, fluorescence microscopy in this spectral window has been limited by the dearth of small\, bright\, and nontoxic NIR-II fluorophores. To address this challenge\, we are investigating a promising class of nanomaterials – DNA-templated silver clusters (Ag-DNAs) – to develop small\, stable\, and modular NIR-II biolabels with broad applicability for deep tissue imaging. Ag-DNAs represent a diverse palette of fluorophores with sequence-encoded sizes of 10-30 atoms and fluorescence emission wavelengths of 400 – 1\,000 nm. I will discuss our growing understanding of the fundamental properties of Ag-DNAs and our development of a high throughput experimental platform coupled with machine learning frameworks to guide discovery of Ag-DNAs within the NIR spectral windows. Using this approach\, we are expanding the color palette of Ag-DNAs well into the NIR\, with exciting future potential to enable deep tissue imaging applications. \nBiography\nStacy Copp is an Assistant Professor of Materials Science and Engineering at the University of California\, Irvine\, where she holds the Samueli Faculty Development Chair and courtesy appointments in the Departments of Physics and Astronomy and Chemical and Biomolecular Engineering. Her research focuses on harnessing information-encoding macromolecules – DNA\, peptides\, and block copolymers – as building blocks for novel optical and electronic materials. Due to the complexity of these molecular materials\, her work incorporates machine learning and data mining for materials study and design. Copp earned a B.S. in physics and mathematics from the University of Arizona (2011) and Ph.D. in physics from UC Santa Barbara. Before joining UCI in 2019\, she was a Hoffman Distinguished Postdoctoral Fellow at Los Alamos National Laboratory (LANL). Copp’s research has been recognized by awards including the AFOSR Young Investigator (2020)\, L’Oreal USA for Women in Science Fellowship (2018)\, and numerous postdoctoral and graduate fellowships.  \nREGISTER HERE \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/stacy-copp-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/08/STACY_2-copy-300x300-1.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20210506T090000
DTEND;TZID=UTC:20210506T100000
DTSTAMP:20260513T152701
CREATED:20210416T041739Z
LAST-MODIFIED:20210416T041739Z
UID:29270-1620291600-1620295200@leadersinlight.com
SUMMARY:Dan Cojoc\, Ph. D.
DESCRIPTION:Cell Mechanics by Light \nAbstract\nLiving cells are active matter characterized by mechanical properties as stiffness and deformability and morphological parameters as shape and volume. Genetic or pathogenic modifications of these properties can affect cell behavior. Since these transformations are potential indicators in various pathologies\, cell mechanics characterization has progressively gained interest.  However\, due to their variability it is difficult to establish absolute values for these properties\, especially when different measurement methods are applied. In the first part\, I will discuss this issue presenting results obtained with Optical Tweezers (OT)\, Atomic Force Microscopy (AFM) and Digital Holographic Microscopy (DHM) and showing that using more than one type of cell allows to confront the methods\, confirm the results and cell behavior. Cells can detect and respond to pressure and forces exerted by the cellular environment in various forms. Thus\, mechanosensitive signaling pathways are activated\, inducing cytoskeleton reshaping and force generation as a response to these mechanical stimuli. How big and how much localized is the force inducing a mechanical stimulation\, and what is its time extent? These questions are still to be elucidated. In the second part of the talk\, I will argue on the use of OT as an adequate tool to study cell mechanotransduction. Using a novel OT setup\, mechanical stimuli are applied under controlled conditions\, the force and indentation of which are measured directly and precisely. Neuronal cells are locally stimulated with piconewton forces which trigger Ca2+ transients in the cell and induce cytoskeletal modifications. \nBiography\nDr. Dan Cojoc is a Senior Scientist at the Institute of Materials of the National Research Council of Italy (CNR). With a background in Optical Engineering (M.S.) and Technical Physics (Ph.D.) from the University “Politehnica” of Bucharest\, Romania\, he has contributed to develop microscopy devices and techniques for applications in nanotechnology and biophysics. He has created various optical tweezers setups for sample manipulation and force measurements and integrated them with X-ray diffraction\, holographic microscopy\, laser microsurgery and fluorescence imaging for the study of biological samples. Currently\, Dr. Cojoc’s laboratory applies optical tweezers and digital holographic microscopy techniques to probe cell mechanics of blood\, cancer and neuronal cells. The interaction of light with the matter is exploited to apply tiny forces to cells and measure their local deformations to derive the mechanical properties or examine mechanotransduction mechanisms. Dr. Cojoc has been engaged in several interdisciplinary projects and has been awarded with research grants and fellowships from Italy\, Croatia\, Spain\, Germany\, France\, Romania and China. He published more than 130 papers\, keeps 3 patents\, is co-author of 11 chapter books and reviewer for more than 10 scientific journals. Dr. Cojoc is an adjunct professor at the University of Trieste and at the International School of Advanced Studies (SISSA) Trieste\, lecturing Experimental Biophysics and Advanced Optical Microscopy courses for undergraduates and tutoring PhD students in Nanotechnology and Neurobiology programs.  \n  \nREGISTER HERE \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/dan-cojoc-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/04/Dan-Cojoc.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20210422T120000
DTEND;TZID=UTC:20210422T130000
DTSTAMP:20260513T152701
CREATED:20210416T014528Z
LAST-MODIFIED:20210416T014528Z
UID:29266-1619092800-1619096400@leadersinlight.com
SUMMARY:Nozomi Nishimura\, Ph. D.
DESCRIPTION:In vivo multiphoton microscopy of microvasculature and inflammation: Lessons from the brain and a look at the heart  \nAbstract\nIn vivo multiphoton microscopy enables the visualization of dynamics at the cellular scale and is an ideal tool for studying the interactions of cells in vivo. Such imaging has revealed the importance of maintaining vascular health\, even in the smallest blood vessels and the capillary bed. In an example in the brain\, we found in mouse models of Alzheimer’s disease (AD)\, that stalled blood flow in a small number of capillaries caused by neutrophils plugs had a surprisingly large effect on total blood flow. Rescue of blood flow led to rapid improvements in short-term memory. We also used laser-induced lesions to study the effects of small-vessel occlusions on inflammation and on amyloid-beta deposits. We discovered rapid alterations in plaques\, both dissolution and increase in deposits\, that were previously thought to be stable structures. We recently adapted these experimental capabilities to organs with motion including the heart. In models of heart failure\, intravital imaging of cardiac vasculature suggests that leukocyte obstruction of capillaries may play a role in the disease. Intravital vital imaging also enables measurements of calcium dynamics and contraction in cardiomyocytes and concurrent dynamics in inflammatory cells. \nBiography\nNozomi Nishimura is an Associate Professor in the Meinig School of Biomedical Engineering at Cornell University and develops optical tools for studying in vivo cell behaviors in disease. Her PhD is in physics from the University of California at San Diego with Prof. David Kleinfeld where she studied blood flow in the brain of rodents and developing laser-based models of small stroke. She came to Biomedical Engineering at Cornell in 2006 to do a postdoc with Prof. Chris Schaffer and later joined the faculty in 2013.To study the complex actions of cells in vivo\, her lab develops intravital multiphoton microscopy imaging methods that reveal how cells function\, move and interact. Injury triggers the recruitment and activation of many immune and inflammatory cell types that\, together with the local cells\, determine the course of the disease progression. The goal is to develop methods to visualize all of these cells at once and quantify cell actions and function. She applies these tools in many systems\, but has particular interests in studying the effects of microvascular dysfunction in the brain. Her lab studies the role of microvascular occlusions in Alzheimer’s disease and neurodegeneration. These methods were recently adapted for the beating mouse heart providing new capabilities to study single cell function and cardiac microvasculature. Recent work expanding into the intestine revealed novel behaviors such as motion and force actuation by stem cells in response to injury.\nSponsored by the Berns Family LAser and Microbeam Program \n  \nREGISTER HERE \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/nozomi-nishimura-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/04/Nishimura.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20210401T120000
DTEND;TZID=UTC:20210401T130000
DTSTAMP:20260513T152701
CREATED:20210225T054811Z
LAST-MODIFIED:20210225T055556Z
UID:29190-1617278400-1617282000@leadersinlight.com
SUMMARY:Ji-Xi Cheng\, Ph. D.
DESCRIPTION:Harnessing Photons for Label-free Chemical Imaging\, High-Precision Neuromodulation\, and Killing of Superbugs  \nAbstract\nPhotons are unique in that they can directly interact with molecules\, the foundation of life. I will give an overview of our biophotonics research at three levels of interactions. At the weak interaction regime\, I will present label-free chemical microscopy utilizing spectroscopic signals for discovery of molecular signatures related to cancer aggressiveness and antimicrobial resistance. At the moderate interaction regime\, I will present non-genetic high-precision optoacoustic stimulation of nervous system. At the strong interaction regime\, I will show that photolysis of intrinsic chromophores could effectively sensitize resistant pathogens to antibiotics and anti-fungal drugs. \nBiography\nJi-Xin Cheng is currently the Inaugural Theodore Moustakas Chair Professor in Photonics and Optoelectronics at Boston University. Cheng and his team are constantly at the forefront of chemical imaging in innovation\, discovery\, commercialization\, and clinical translation. For his pioneering contributions to the field of vibrational spectroscopic imaging\, Cheng received the 2020 Pittsburg Spectroscopy Award from the Spectroscopy Society of Pittsburg\, the 2019 Ellis R. Lippincott Award from OSA\, Society for Applied Spectroscopy\, Coblentz Society\, and the 2015 Craver Award from Coblentz Society. Cheng is authored in over 270 peer-reviewed articles with an h-index of 79 (Google Scholar). His research has been supported by over 30 million ($) fund from federal agencies including NIH\, NSF\, DoD\, DoE and private foundations including the Keck Foundation. Cheng is a Fellow of Optical Society of America\, a Fellow of American Institute of Medicine and Biological Engineering\, and associate editor of Science Advances. \n  \nREGISTER HERE \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/ji-xi-cheng-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/02/Ji-Xin-Cheng-Headshot.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20210324T100000
DTEND;TZID=UTC:20210324T110000
DTSTAMP:20260513T152701
CREATED:20210220T050239Z
LAST-MODIFIED:20210220T050956Z
UID:29168-1616580000-1616583600@leadersinlight.com
SUMMARY:Dr. Christoph Hitzenberger\, Ph. D.
DESCRIPTION:From Ocular Biometry to Cellular Resolution – and Multifunctional OCT – Coherence Ranging and Imaging in the Human Eye over 35 Years \nAbstract \nIn the mid 1980s\, first applications of low coherence interferometry (LCI) to tissue metrology and analysis were reported. Starting from one-dimensional ocular biometry\, the technology has evolved into a high-speed\, 3-dimensional imaging technology\, now known as optical coherence tomography (OCT)\, with a multitude of functional extensions that has revolutionized ocular diagnostics. This talk illustrates the evolution of the technology over a third of a century\, as seen from a Viennese perspective. Starting with first axial eye length measurements by LCI\, a bridge is spanned to modern high-speed\, high-resolution\, and multifunctional OCT\, including some examples of current research in the OCT labs at Medical University of Vienna. \nBiography \nChristoph K. Hitzenberger is Professor of Medical Physics and Vice Chair of the Center for Medical Physics and Biomedical Engineering\, Medical University of Vienna\, and Editor-in-Chief of Biomedical Optics Express. He works in Biomedical Optics since 1987 and is one of the pioneers of low coherence ocular biometry and optical coherence tomography. Among his most important contributions to these fields were the introduction of the optical A-scan in 1990\, the first demonstration of Fourier domain OCT methods in 1995\, and pioneering work in polarization sensitive OCT since 2000. He is Fellow of OSA and of SPIE; his pioneering contributions to OCT were awarded with the Russ Prize of the US National Academy of Engineering in 2017 and with the Austrian Cross of Honour for Science and Art\, First Class. \n  \nREGISTER HERE \n  \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/ocular-biometry/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2021/02/hitzenberger-headshot.jpg
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=UTC:20201119T120000
DTEND;TZID=UTC:20201119T133000
DTSTAMP:20260513T152701
CREATED:20201117T045353Z
LAST-MODIFIED:20201120T071341Z
UID:28928-1605787200-1605792600@leadersinlight.com
SUMMARY:Muyinatu Bell.\, Ph.D.
DESCRIPTION:Assistant Professor & PULSE Lab Director – Johns Hopkins University \nDepartment of Electrical and Computer Engineering\nDepartment of Biomedical Engineering \nListening to the Sound of Light to Guide Surgeries \nAbstract\nPhotoacoustic imaging offers “x-ray vision” to see beyond tool tips and underneath tissue during surgical procedures\, yet no ionizing x-rays are required. Instead\, optical fibers and acoustic receivers enable photoacoustic sensing of major structures – like blood vessels and nerves – that are otherwise hidden from view. The entire process is initiated by delivering laser pulses through optical fibers to illuminate regions of interest\, causing an acoustic response that is detectable with ultrasound transducers. Beamforming is then implemented to create a photoacoustic image. In this talk\, I will highlight novel light delivery systems\, new spatial coherence beamforming theory\, deep learning alternatives to beamforming\, and robotic integration methods\, each pioneered by the Photoacoustic & Ultrasonic Systems Engineering (PULSE) Lab to enable an exciting new frontier of photoacoustic-guided surgery. This new paradigm has the potential to eliminate the occurrence of major complications (e.g.\, excessive bleeding\, paralysis\, accidental patient death) during a wide range of delicate surgeries and procedures\, including neurosurgery\, cardiac catheter-based interventions\, liver surgery\, spinal fusion surgery\, hysterectomies\, biopsies\, and teleoperative robotic surgeries.  \nBiography\nMuyinatu Bell is an Assistant Professor of Electrical and Computer Engineering\, Biomedical Engineering\, and Computer Science at Johns Hopkins University\, where she founded and directs the Photoacoustic and Ultrasonic Systems Engineering (PULSE) Lab. Dr. Bell earned a B.S. degree in Mechanical Engineering (biomedical engineering minor) from Massachusetts Institute of Technology (2006)\, received a Ph.D. degree in Biomedical Engineering from Duke University (2012)\, conducted research abroad as a Whitaker International Fellow at the Institute of Cancer Research and Royal Marsden Hospital in the United Kingdom (2009-2010)\, and completed a postdoctoral fellowship with the Engineering Research Center for Computer-Integrated Surgical Systems and Technology at Johns Hopkins University (2016). She is Associate Editor-in-Chief of IEEE Transactions on Ultrasonics\, Ferroelectrics\, and Frequency Control (T-UFFC)\, Associate Editor of IEEE Transactions on Medical Imaging\, and holds patents for short-lag spatial coherence beamforming and photoacoustic-guided surgery. She is a recipient of multiple awards and honors\, including MIT Technology Review’s Innovator Under 35 Award (2016)\, the NSF CAREER Award (2018)\, the NIH Trailblazer Award (2018)\, the Alfred P. Sloan Research Fellowship (2019)\, the ORAU Ralph E. Powe Jr. Faculty Enhancement Award (2019)\, and Maryland’s Outstanding Young Engineer Award (2019). She most recently received the inaugural IEEE UFFC Star Ambassador Lectureship Award (2020) from her IEEE society. \n  \nREGISTER HEREDr. Muyinatu Bell\, Ph.D. \n  \nSponsored by the Michael and Roberta Berns Laser Microbeam Program
URL:https://leadersinlight.com/event/muyinatu-bell-ph-d/
LOCATION:Zoom Event\, CA\, United States
CATEGORIES:LAMP Seminar
ATTACH;FMTTYPE=image/jpeg:https://leadersinlight.com/wp-content/uploads/2020/11/MuyinatuBell.jpg
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