Startups & Innovations: New Hires

By Jessie Yount, Orange County Business Journal

Modulim has named Charlie Huiner chief executive.

Huiner comes from the Irvine-based firm after nearly six years with Santa Barbara-based Sientra, Inc. (NASDAQ: SIEN), where he helped raise $375 million in equity financing including a successful IPO.

In his new role, Huiner will oversee Modulim’s Series C fundraising efforts and lead commercial strategy for its Clarifi imaging device, the company said.

“With Charlie’s experience and expertise, we are poised to build from a number of key milestones recently achieved by the Company to accelerate commercialization,” said Chief Technology Officer David Cuccia.

Modulim received CE Mark certification this month for its noninvasive, radiation-free imaging system, which produces images that resemble a thermal heat map.  Warmer colors signal better blood perfusion, while darker ones indicate low oxygenation.

The company’s product is largely focused on diagnosing and preventing the effects of diabetic foot ulcers.

Cuccia invented Modulim’s imaging technology at the UCI Beckman Laser Institute and introduced Clarifi to the U.S. market last fall.

The company has raised more than $21 million in public and private funds to date.

Read the full Orange County Business Journal article.

2021 SPIE-Franz Hillenkamp Postdoctoral Fellowship Awarded to Nitesh Katta

The annual award will support the development of Katta’s doctoral research, as well as his efforts to translate benchtop advancements into clinical successes

BELLINGHAM, Washington, USA — SPIE, the international society for optics and photonics, has announced Nitesh Katta, who received his PhD in 2019 from the University of Texas at Austin, as the winner of the 2021 SPIE-Franz Hillenkamp Postdoctoral Fellowship in Problem-Driven Biomedical Optics and Analytics. The annual award of $75,000 supports interdisciplinary problem-driven research and provides opportunities for translating new technologies into clinical practice for improving human health.

Katta’s research project, “A cold laser wire (CLW) for true-lumen crossing of tortuous coronary arteries with calcified chronic total occlusions (CTOs)” — conducted in conjunction with Thomas Milner and Marc Feldman at the Beckman Laser Institute and Medical Clinic — will build on a challenge Katta discovered during his doctoral work: in recognizing an unmet need for piercing calcified material in performing true-lumen percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs), Katta, together with his then-doctoral mentors Milner and Feldman, invented intravascular cooling and guidance methodologies for achieving true-lumen crossing in CTOs using the cold laser wire. Katta’s aim is to bring this research into the clinical setting, addressing an urgent clinical need of a tool for safe PCI in patients suffering with CTOs.

“I am deeply grateful to receive this support from such a distinguished organization as SPIE and feel very humbled to have the SPIE-Hillenkamp fellowship committee recognize the value of this work,” says Katta. “Receiving this award will enable me to conduct the necessary research work and translational training to bring a medical device from a laboratory bench-top to the market where it can have a meaningful impact on percutaneous coronary intervention outcomes in patients suffering from chronic total occlusions.”

“This is a very exciting proposal from an excellent researcher working in a renowned lab for innovative research in biomedical optics and biophotonics that translates into solving medical problems,” said the Co-Chairs of the Hillenkamp Fellowship Committee Rox Anderson and Gabriela Apiou. “Nitesh’s work has the potential to establish a new class of simple and safe methods to operate endovascular light-based therapeutic devices, and we look forward to seeing the outcome of his work.”

Honoring the career of medical laser pioneer Franz Hillenkamp, the SPIE-Hillenkamp Fellowship is a partnership between multiple international biomedical laboratories — the Wellman Center for Photomedicine, the Beckman Laser Institute, the Manstein Lab in the Cutaneous Biology Research Center at Massachusetts General Hospital, Medical Laser Center Lübeck, and Boston University — and the Hillenkamp family. The endowment is funded through generous donations from the biomedical optics community, with SPIE contributing matching funds up to $1.5 million.

About SPIE

SPIE is the international society for optics and photonics, an educational not-for-profit organization founded in 1955 to advance light-based science, engineering, and technology. The Society serves more than 258,000 constituents from 184 countries, offering conferences and their published proceedings, continuing education, books, journals, and the SPIE Digital Library. In 2020, SPIE provided over $5.8 million in community support including scholarships and awards, outreach and advocacy programs, travel grants, public policy, and educational resources. www.spie.org.

Read full SPIE press release.

Modulim Announces Seasoned Medical Device Executive Charles Huiner as Chief Executive Officer

Irvine, CA—Modulim, the global leader in optical imaging solutions for the non-invasive assessment of tissue and vascular health, today announced that Charles Huiner has been named President and Chief Executive Officer (CEO). Huiner will start immediately and lead the Company’s Series C fundraising and execution of a focused growth strategy for its FDA-cleared product, Clarifi®.

Huiner brings over 25 years of executive experience with a successful leadership track record across multiple life science market segments including biotech, medical devices, and digital health. Most recently, he served as Chief Operating Officer and Senior Vice President, Corporate Development and Strategy for Sientra, Inc. (NASDAQ: SIEN), a global medical aesthetics company with annual revenues exceeding $80 million. While serving at Sientra, he authored the company’s growth strategy, led several key acquisitions, and helped execute $375 million in equity financing including a successful IPO. Prior to that, he was Vice President of Marketing and Business Development at InTouch Health during a transformative period that solidified the company’s market strategy and commercial model, leading to its eventual $600 million exit to Teladoc Health. Previously, as Senior Director of Corporate Development and Strategy at INAMED, Inc. he was instrumental in broadening the company’s product portfolio that contributed to its $3.3 billion acquisition by Allergan Aesthetics.

“It’s fantastic to have Charlie on-board to lead Modulim’s next phase,” said David Cuccia, Modulim’s Founder, Board member and Chief Technology Officer. “With Charlie’s experience and expertise, we are poised to build from a number of key milestones recently achieved by the Company to accelerate commercialization. The whole executive team looks forward to working with him to enact Modulim’s mission—to deliver transformative optical solutions that help people live healthier, longer lives.”

“I am excited for the opportunity to lead Modulim’s talented team. The Company will play a significant role in the ongoing convergence of medical diagnostic, predictive AI, and telehealth technologies to enable more efficient healthcare delivery. Our decision support solutions are applicable to numerous ill-met chronic conditions and vascular complications, starting with helping healthcare providers prevent costly and often deadly undiagnosed conditions brought on by diabetes and peripheral arterial disease,” said Huiner. “I look forward to working with my new colleagues to accelerate the adoption and expansion of our proprietary SFDI technology while improving the lives of patients.”

“We are pleased to have attracted a high caliber, proven executive like Charlie to strengthen the Company and advance on early successes with strategic customers,” said Janelle Goulard, Partner at Pangaea Ventures. “Charlie brings extensive technology commercialization knowledge and experience at this dynamic period of growth for Modulim. We believe the Clarifi solution will positively impact millions that are living with chronic conditions.”

About Modulim
Modulim is a privately held medical device company founded by the inventors of SFDI at the University of California Irvine with a team dedicated to delivering powerful healthcare solutions that elevate and standardize health care delivery, while improving patient outcomes. Its mission is to deliver transformative optical solutions that help people live healthier, longer lives. Clarifi, powered by Spatial Frequency Domain Imaging (SFDI) technology, identifies compromised

Meet The World’s Newest – And Youngest – Self-Made Billionaire: Luminar’s Austin Russell

By Alan Ohnsman and Alexandra Sternlicht, Forbes

The race to commercialize self-driving car technology has attracted billions of dollars of investment but not created many billionaires. Luminar founder and CEO Austin Russell is among the rare exceptions. With today’s Nasdaq listing of the laser sensor company he founded at age 17, the optics prodigy is one of the first billionaires to emerge from the autonomous vehicle world–and the youngest self-made billionaire in the world.

“It’s been insanely intense, grueling … everything through every day that we’ve had to go through scaling this up. And of course it’s incredibly rewarding to have an opportunity to be able to get out there now and get into the public markets and scale through this IPO SPAC,” 25-year-old Russell tells Forbes in a video interview from his office in Palo Alto, California. “I’m still relatively young, but … a lot of blood, sweat and tears have gone into it. And I was fortunate enough to be able to retain a good enough stake.”

Good enough indeed. Russell’s 104.7 million shares, about a third of Luminar’s outstanding equity, is worth $2.4 billion at the start of Nasdaq trading today. The listing, announced in August, resulted from a merger with special purpose acquisition company Gores Metropoulos, a unit of Beverly Hills-based finance firm The Gores Group, and raised Luminar’s estimated market value to $3.4 billion. Investors in the newly public company include fellow billionaire Peter Thiel (net worth: $4.6 billion), who helped get Russell started with Luminar by making him a Thiel Fellow in 2012; Volvo Cars Tech Fund; Alec Gores of The Gores Group, another billionaire ($2.2 billion) who is also a Luminar board member; and billionaire Dean Metropoulos, the company’s chairman.

Thiel, the Paypal cofounder who famously created a fellowship offering extraordinary young people $100,000 to drop out of college to pursue their dreams, has been an advisor to Russell since he left Stanford to start Luminar in 2012. As a mentor, Thiel is impressed not just by the new tech billionaire’s intellect, but his ability to hold onto a significant chunk of Luminar as it moved from Russell’s garage concept to Nasdaq.

“You can build a billion-dollar business but that does not mean you can become a billionaire,” says Thiel. “It’s remarkable from a financing perspective to retain a financial stake of that size.”

Russell, who’s also a Forbes 30 Under 30 alum from the class of 2018, isn’t looking to take on self-driving tech giants like Alphabet’s Waymo or GM-backed Cruise, but instead is perfecting sensors that help autonomous cars “see” their surroundings by bouncing a laser beam off objects in their path. Known as Lidar for “light detection and ranging,” the technology is fundamental for autonomous vehicles and Luminar is competing in that space with Velodyne, the early leader in lidar for autonomous vehicles, and newcomer Aeva, both of which are also going public via SPAC mergers. Russell has sold prototype sensors to major auto companies for the past few years, but more recently secured production orders from Volvo Cars, Daimler and Intel’s Mobileye that may ensure revenue growth for several years.

Luminar will likely post sales of just $15 million this year, but could generate at least $1.3 billion by 2026, based on estimates in an SEC filing.

Russell’s abilities extend beyond the lab to the boardroom, according to Alec Gores, who helped arrange Luminar’s listing. “When we were negotiating, he was so on the top of everything, the small details. 60-year-old guys who’ve been in the business for 40 years don’t understand this stuff, but he took time to study the SPAC,” he says. “I’m looking at this guy and saying, ‘you asked more questions than anybody I’ve seen that’s been doing this sh*t for a long time.’”

The lanky 6’4” Russell, with shaggy strawberry blonde hair and a light beard to match, was making notable achievements long before his new billionaire status. As the story goes, he memorized the periodic table of elements at 2 years old and rewired his Nintendo DS game console into a crude mobile phone when he was in the sixth grade after his parents forbade him from having one. At 13, he filed his first patent: an underground water recycling system that catches sprinkler water and saves it for future gardening to reduce wastewater. Rather than go to high school, he spent his teen years at the University of California, Irvine’s Beckman Laser Institute.

Next came admission to Stanford to study physics, but that didn’t last long. He dropped out midway through his freshman year after winning a $100,000 Thiel Fellowship stipend for his lidar concept, founding Luminar not long after obtaining his driver’s license.

Excluding inherited fortunes, Russell is ​one of about a dozen people on the planet to make a billion dollars before they turned 30.

Lidar was an early fixation for Russell as he believes it has the potential to save lives both as part of self-diving cars and as a component of advanced driver-assistance systems that Volvo and other carmakers are bringing to market in the next two to three years. As a teenager, he’d looked at what Velodyne and other companies were doing with laser sensors, but determined a completely different approach was needed to make them cheap enough to be ubiquitous.

“It should not be a 16- or 17-year-old, and then subsequently a 25-year-old that can build a business like this,” says Russell. “We’ve been able to accelerate this because no one has really done this before.”

It doesn’t hurt that Russell has zero distraction from social media or time-sucking general education requirements of college and high school degrees. Unlike most 25-year-olds, he has neither Twitter nor Instagram accounts, but confesses to learning most of what he knows about the world from avid Wikipedia and YouTube explainer consumption.

As a Gen Y billionaire, Russell is also thinking about his impact. Though he has no immediate plans for Gates-like philanthropy, he sees his contribution as eradicating automobile accidents. “When this becomes a new, modern safety technology on vehicles that’s integrated on every vehicle globally produced, that’s when I’d firmly say that we’ve accomplished the goals that we set.”

Read full “Forbes” article.

ACES Summer Program Goes Viral

High-achieving, underrepresented students get a glimpse of graduate school

This past summer, the Institute hosted 10 students for the virtual Access to Careers in Engineering and Sciences (ACES) program. The UC Office of the President-supported Historically Black Colleges and Universities (HBCU) partner program funds this summer training initiative. The program introduces high-achieving, underrepresented undergraduate students to the possibilities of graduate education and the breadth of UC Irvine graduate programs in the fields of biomedical engineering, biophotonics and related Science, Technology, Engineering and Math (STEM) disciplines.

ACES has resulted in the acceptance of five talented Black students to University of California campuses in STEM Ph.D. programs. Breyah Matthews joined the UC Irvine Advanced Power and Electricity program in the Department of Electrical Engineering and is entering her third year of graduate study. Alexius Lampkin was accepted at UC Davis, but chose to attend University of Wisconsin as a Ph.D. student in Chemistry. In addition, Chris Johnson, Lauryn Alexander and Jakari Harris were accepted into Ph.D. programs at UC Irvine. Chris is in his second year in the UC Irvine Department of Biomedical Engineering. Lauryn matriculated at West Virginia University to pursue a Ph.D. in Forensic Sciences and Jakari Harris enrolled in a joint Ph.D. program in Biomedical Engineering at Georgia Tech/Emory University.